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History

The Beginning

1897

The Beginning

In a Bayer laboratory in Wuppertal, Germany, young scientist Dr. Felix Hoffmann is the first to succeed in synthesizing a chemically pure and stable form of acetylsalicylic acid (ASA), which becomes the active ingredient in Aspirin. [49]

Trademark

1899

Trademark

Aspirin™ is registered as a trademark. It is launched on the market in powder form. Bayer delivers the medicine to pharmacies in small 250-gram glass vials. 500 mg of the powder is then weighed out and dispensed to customers in small paper bags. Just one year later, Bayer launches the analgesic in its classic tablet form – one of the first medicines to be marketed in this dosage form. [49]

Apollo 11

1969

Apollo 11

A box of Aspirin™ flies to the moon aboard Apollo 11 [49]

Stroke Prevention

1978

Stroke Prevention

A study published in the “New England Journal of Medicine” shows that aspirin can reduce the stroke or death in men. [48]

Nobel Prize

1982

Nobel Prize

British pharmacologist Sir John Vane was awarded the Noble Prize in Physiology or Medicine for his discovery that the anti-inflammatory properties of aspirin result from its ability to inhibit the body’s production of certain chemical mediators (prostaglandins) that promote inflammation. [39, 49]

Heart Attack Prevention

1985

Heart Attack Prevention

The US Food and Drug Administration approves aspirin (under a doctor’s direction) for prevention of a second heart attack. [63] 

Research

1989

Research

Publication of Physician’s Health Study (PHS), which demonstrated a significant reduction in first heart attack in healthy male subjects taking aspirin. [47]

Cardiovascular Uses

1998

Cardiovascular Uses

The US Food and Drug Administration approves expanded cardiovascular professional labeling for aspirin. indications now include use of aspirin (as directed by a physician) during a suspected heart Attack at confirmed high risk patients , preventing a recurrent ischemic stroke or transient ischemic stroke in men and women. [2, 46] 

Anniversary

1999

Anniversary

Aspirin celebrates the 100th anniversary of its patent [53, 58]
Aspirin is also inducted into the Smithsonian Institution’s National Museum of American History, USA. [45]

The Future

3027

The Future

Aspirin is seeking new ways to innovate and drive its product line forward for you. [62]